vaccine effectiveness

Similar to PV-based systems, VLPs have also seen extensive use in vaccine development, propelling advancements in vaccination against infections as well as tumors. Applications of VLP-based systems range from neutralizing antibody screening to evaluation and validation of candidate vaccine compositions.

Advantages of VLP-based vaccine development

1. Rapid production of VLP enabling for large-scale vaccine manufacture and high-throughput screening;

2. Highly encompassing nature of VLP allows for development of multi-valent vaccines targeting sites that are not easily accessible by conventional ones;

3. Safe and accessible handling attributed to the absence of essential virulence gene;

4. Easy manipulation/modification allowing for purposefully constructed VLP assemblies.